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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Global emissions of greenhouse gases jumped 2.3 percent in 2013 to record levels, scientists reported Sunday, in the latest indication that the world remains far off track in its efforts to control global warming.
2020年,10美元钞票上将出现一名著名美国女性的画像。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

"According to our survey last year, only 0.6 to 0.7 percent of students at universities were thinking about starting their own companies. The number among vocational school students was as high as 2.2 percent. However, the idea of vocational students starting businesses is related more to creating jobs for themselves, and the majority of them have chosen to have online shops."
8.Wheel Skates

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Martial art “China Youth”(Zhao Wenzhuo and friends)

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

与此同时,还有其他因素在掣肘亚洲ETF市场,一些怀疑者担心,这些因素将阻碍散户市场的发展。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

在做完所有他能做的自救措施后,这个务实的孩子不知道还要多久才会有人来救他,于是他决定做家庭作业。
The World Health Organization this year declared H1N1 a global epidemic. Fortunately, it is much less threatening than people previously believed, and newly introduced vaccines seem to have quelled lingering fears.
二,7月与空客和国家发改委签署谅解备忘录后,上月份商飞以一份十年期债务投资计划成功融资150亿人民币。融资和签署备忘录旨在帮助形成一个成熟的、有竞争力的国内供应链,前者通过注入研发资金,后者通过整合中国供应商在空中客车的全球供应网络。“中国制造2015”计划中提到,到2025年中国供应商有望能提供80%的飞机零部件。
米其林(Michelin)、微软(Microsoft)、爱立信(Ericsson)等大企业的领导人已经把更多的决策权推向一线员工。随着这种方法的成功引起注意,其他企业将效仿。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

The pandas did some tai-chi in Trafalgar Square before kicking on at a panda party in Convent Garden as part of the first ever Panda Awareness Week.
学校获得的好处似乎显而易见:它们有了优秀的毕业生任教,否则这些学生将会直接进入咨询行业。
1、阅兵仪式
时间:2009-10-29 编辑:vicki

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 工行6000亿融资支持租房市场
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

打造众创、众包、众扶、众筹平台

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The second most sought-after job, according to Zhonggong, was a position offered by the regional earthquake bureau in the Inner Mongolia autonomous region, which had 768 applicants as of Tuesday.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

社交客服将杀死可怕的电话树
认为西方民主政体不会受影响将是愚蠢的。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 满足棚改货币化补偿市民购房需求
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

我们不希望看到打贸易战,贸易战带不来贸易公平,而且双方都受损。
3.人工胰腺

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 山东莱西提升城市能级
Open Access Review Article

Diagnostic technologies for COVID-19: a review

He also has serious thrill issues dude.
最佳电影提名应该可以肯定。参演《至暗时刻》的加里?奥德曼是最佳男主角的最热人选,如果说有谁能击败他的话,那可能就是蒂莫西?柴勒梅德了。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 扶贫搬迁安置点地基塌陷,问责!
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

The scientists’ analysis comes only a month after nearly 200 governments struck a new climate agreement in Paris that aims to stop global temperatures from rising more than 2C from pre-industrial levels, and ideally limit warming to 1.5C.
位居榜单第三的是史蒂夫·卡瑞尔(Steve Carell)。《卑鄙的我2》(Despicable Me 2)在今年大获成功,斩获票房9.19亿美元。该电影系列累计已取得14亿美元的全球票房,该系列第三部《小黄人》(Minions)也即将上映。卡瑞尔今年还出演了小制作独立影片《迷途知返》(The Way Way Back)和《超级魔术师》(The Incredible Burt Wonderstone)。后一部影片的票房虽未能赚回制作成本,但是我们这里只关注票房收入——该部影片为卡瑞尔2013年的电影票房收入又添2,250万美元。
根据中国海关总署(General Administration of Customs)的数据,在经历了此前一个月的同比下跌1.4%之后,11月份中国的进口同比增长6.7%,至1522亿美元,远高于同比收缩1.9%的预测中值。
补救办法:当我们在做出重大决定时,例如接受(或拒绝)工作邀请时,我们往往会受到信息性偏见的影响。如果我们认为自己做出了正确的选择,就首先会想到那些支持这种想法的信息。但如果我们担心自己犯了错误,我们的潜意识就会增强这种直觉。在做出工作的决定时,如果你习惯性地怀疑自己的能力,这个问题不在于你以前所做的职业选择是否正确,而在于你需要建立自信,相信自己有能力选择让自己满意的职业,并对结果有一定的把握。若要解决这个问题,需要回忆你在做出这个选择时所处的环境和当时你所优先考虑的因素,然后看看现在所处的环境和优先考虑的因素是否发生了变化。此外还要与职业顾问合作,理清工作决策,帮助你增强进入新领域的信心、承担风险和谈判的能力。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

质量强国、制造强国

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

会。梅因为失算的提前选举而失去了大部分权威。但过去几个月情况对她较为有利。敲定退欧离婚协议,确保了她的饭碗短期无忧。因此直到2019年英国退欧正式完成(或者另一种更吸引人的替代方案出现)前,保守党将让她继续坐在首相位置上。留欧派和退欧派都希望避免因反对她而引发内战。事实将证明,曾经被人们认为是坐不长的位置,意外地能够坐久。
I'm only a child yet I know we are all in this together and should act as one single world towards one single goal. 我身为小孩都知道,我们在地球的母亲怀中都是孩子。我们应该为了相同的目的进行相同的行动!

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 业主们 这些隐形收益你们知道吗
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

“即便人们充分了解了(美联储政策的作用),市场动态也可能相对容易地变得不稳定或不利,”他说,“届时你将陷入一个卖盘压力自我强化的循环。”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

可口可乐表示,中国消费放缓打击了销售额,而较为疲弱的需求正迫使其降低库存。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

在苹果公司外面,摆着一台显示乔布斯照片的iPhone ,用以寄托对这位苹果创始人和前CEO的哀思。2011年10月6日,旧金山,苹果总部
2016年,我们看到很多新设备加入互联网(不幸的是,我们也看到他们被黑客打倒了大片)。从家用电器到服装,公司很想出售一些能使你的生活“智能化”的产品,但有时反而会适得其反。让我们来回顾在过去的一年里出现的一些最荒谬和最无用的互联网连接设备。
"Metro-Goldwyn-Mayer Inc. ('MGM') today announced that the secured lenders voting in the Company's solicitation process have overwhelmingly approved its proposed plan of reorganization ('Plan'). MGM will now move expeditiously to implement that Plan, which will dramatically reduce its debt load and put the Company in a strong position to execute its business strategy. MGM is appreciative of the lenders' support."
?The Aston Martin doesn't hurt. Not at all. Neither does dropping tons of cash at exotic casinos -- throwing money around makes men more attractive to women who are interested in flings. And, like Bond, men who gamble with women around are better at it.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

?Bond has a keen eye for who to trust and who not to. This quality is frequently seen in sexually open-minded people, actually. 007 can tell when a lady is into him. And science agrees: handsome men are the best at identifying who is attracted to them.
Hannah Kuchler is San Francisco correspondent
泰勒 斯威夫特
在一些女学生通过提供裸照作为交换,在互联网借贷平台上获取高息贷款之后,近日又有大批裸照被泄露在了互联网上。
可口可乐正在改组其业务,出售其在美国以及全球的瓶装业务,转而专注于生产其很多饮料使用的浓缩汁,以及研发。这些资产出售将让该公司将更多资源投入创新和收购。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

从一个孩子的视角,讲述佛罗里达州一家汽车旅馆社区的生活。
劳瑞斯蒂尔

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

《盗墓笔记》

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

"The editors thought the articles were being sent out to genuine reviewers in the discipline," he said. "Following our investigation and communication with the real reviewers, they confirmed they did not conduct the peer review."

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

然而,《秦时明月丽人心》并不能让更喜欢真实历史而非虚构故事的观众满意,该剧豆瓣评分仅为4.9分。
"Perhaps it is no big deal whether or not you are in the group discussion, but if you were absent, 670,000 people would be absent, if you were silent, 670,000 people would be silent."
The immediacy for a larger-screen iPhone comes partially from the Asian market where Samsung’s phablets have made significant inroads. Assuming that Apple’s agreement with China Mobile includes these upcoming products, the pricing adjustments that normally occur with new iPhones could make the iPhone 5C significantly more affordable and attractive to the Chinese market. This would begin to make sense of the 5C, which so far seems to be a sales disappointment for Apple. Perhaps the important thing about the 5C is that it is not the 5S, so that down the road it can be discounted without putting price pressure on Apple’s flagship.
Andrew Hill is management editor

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

英国会是七国集团(G7)中经济增长最慢的国家吗?
8. How to dip dye hair
这篇文章指出,食用有益于心脏的食物是防止痴呆、保护记忆力的关键。一些心脏病的并发症和阿尔茨海默症以及痴呆症的并发症十分相似,因此研究阿尔茨海默症和痴呆症的教授们认为,有益于心脏的食物大概也有益于大脑和记忆。水果、蔬菜、全麦面包、豆子、坚果和橄榄油都有对心脏有益。如果这10个方法你不能都采用的话,一个健康的饮食至少能让你不要丢失记性。
流通量小也助长了给猴年邮票创纪录的价格。在1980年,只有500万“金猴”枚邮票发行,所以现在非常罕见。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

But the duo topped the trending celebrities section followed by 'X Factor' judges Gary Barlow and Tulisa.
purchase

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Manufacturing has held up better, with profits growing 6.5 per cent, while profits from utilities such as electricity, heat and water grew 17 per cent, boosted by lower energy prices.
But John Davies, head of institutional investment in the Hong Kong team at CBRE, the property services business, says that lower prices should make the market more reliable. “The market is showing characteristics of a mature market, which institutional investors understand better,” he says.
照片左起分别是苹果董事长史蒂夫乔布斯,总裁兼CEO约翰斯卡利,创始人之一的斯蒂夫沃兹尼亚克,他们正在推出新款苹果II c型机,1984年4月24日,旧金山
Chinese manufacturers:Coming to the U.S.? Warren Buffett’s BYD says it is arriving in 2015 and Geely in 2016 but we’ve been hearing that someone was coming since at 2006. The refinement of Chinese cars is the issue. With more than 80 local automakers producing 524 different models in China, R&D money is spread too thinly to produce meaningful results.
“It’s fundamentally about ‘who are we?’” said Eric Kaufmann, a professor of politics at Birkbeck College, University of London. “What does it mean to be part of this nation? Is it not ‘our’ nation anymore, ‘our’ meaning the ethnic majority?

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Length of program: 24 months
Academics appear to be more interested in the cryptocurrency than ever before. There were 190 white papers published on bitcoin in 2014, up from 55 in 2013. Authors—amateur or otherwise—have also flocked to bitcoin: Amazon lists 437 books about or involving the term “bitcoin” published in 2014, compared to 143 in 2013. (That is based on a subject search, and thus includes less hard-hitting titles like Bitcoin Bimbo 3: Undercover Cop Science Fiction Erotica.) And sports fans this year may not have been able to ignore the inaugural Bitcoin St. Petersburg Bowl, a college football playoff game between North Carolina State and the University of Central Florida. ESPN quickly convertedBitPay’s $500,000 rights fee for the game into U.S. dollars.
不过,这一增幅低于8月份到9月份3个百分点的增加幅度,意味着近期的房地产限购措施或许产生了一定效果。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The letter surfaced in a Pennsylvanian university mailroom earlier this month.
refrigerator

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

单词accurate 联想记忆:
The expansion would be considered impressive in most markets, but it represents an ongoing slowdown for China, the world's second-largest film territory and a continual source of growth for Hollywood for the better part of a decade.
[k?'m?:l]

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

在土耳其问题上,普京表示,他看不到与现任土耳其领导人消除紧张关系的可能性。土耳其不久前击落了一架俄罗斯战机。他说,他非常震惊地看到,土耳其非但没有对其行为做出解释,反而转向北约寻求帮助。
Lady Gaga以5.9千万位列第四,其后是5.45千万的碧昂斯。前者在统计期间演出了66场,也靠与范思哲和MAC的合约获得收入,同时还有她自己的黑色香水。后者与其老公Jay Z的On The Run巡回演唱会通过19天(北美日期),赚得了超过10千万,创造了能与滚石相比较的第一对音乐界夫妻档夜平均的神话。
You might think Hawaiian has it relatively easy, since its flights rarely have to contend with the kind of challenging weather conditions found on the mainland. Hawaiian perennially rates high in on-time performance rankings, topping the most recent DOT list i n September. It recently announced it will branch well beyond its island home with non-stop service to Beijing.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

中国与世界其他地区的贸易10月同比大幅下滑,原材料进口受到尤其沉重的打击,中国投资放缓削弱了这个全球最大商品贸易国的需求。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

其次,尽管人们还守着老的观念,现实却已经发生了变化:供应链管理——也就是确保货物以尽可能低的价格和尽可能高的效率到达目的地——已经成为一项高科技、高风险的行业了。它要求从业者“硬件能力”和“软件能力”缺一不可,而能达到这种要求的人才实在很少。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

愿你拥有新年所有美好的祝福。
For many Western whites, opportunities for achieved identity — the top of the hill — seem unattainable. So their ascribed identity — their whiteness — feels more important than ever.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

这是第二枚被拍卖的诺贝尔和平奖奖牌,得主是第一个获得该奖项的拉美人——1936年诺贝尔和平奖奖牌被授予当年的阿根廷外长卡洛斯·萨维德·拉莫斯。
本麦克兰纳汗(Ben McLannahan)是美国银行业编辑
以下十条就是你找工作时可能露出的“马脚”
单词recommend 联想记忆:

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

12. 最有希望的迹象。有段时间,你会觉得现状已经改善了,人们可以公开大声谈及业内的歧视现象。维奥拉·戴维斯(Viola Davis)出来说话,詹妮弗·劳伦斯(Jennifer Lawrence)公开谈起,自己比片中的合作男星片酬少。“我不想被视为‘难搞’或者‘被宠坏了’,”她在简报《伦尼》(Lenny)中为许多人发言,其中包括许多薪酬更低的人们。
n. 日历,月历,日程表

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Unlike most boy-band dudes going solo, he never sounds like he's sweating to get taken seriously – he never loses touch with the exuberance and swagger he brought to One Direction in the first place. So get used to this man – you'll be hearing a lot more from him.
"We hope the mother will come to us and verify the facts. If it's true that the user is a 13-year-old who spent the money without consent, we can negotiate a refund," the Tencent employee said.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

2016年空前的海外收购潮消耗了中国大量外汇储备,随后监管部门开始严格限制境外交易。今年8月,中国政府出台了新框架,鼓励那些符合北京战略重点的交易,并限制涉及娱乐、体育和豪宅等方面的交易。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Other top ten foreign pictures were Transformers: The Last Knight, Dangal, Pirates of the Caribbean: Dead Men Tell No Tales, and Kong: Skull Island.
中共中央纪律检查委员会表示,中国正准备与其他国家签署更多双边或多边协议,并将加强信息交流和联合调查,尤其是与美国、加拿大和澳大利亚等西方国家在一些重大或独立个案上的合作。
Yes Man is a heartwarming blockbuster that explores what would happen if you answered "yes" to every question in your life. Jim Carrey's character takes on this challenge and ends up learning Korean, taking flying lessons, and getting promoted. He goes from being a pessimistic divorced man to an exciting trendsetter and finds a new girlfriend in the process. It might sound like fiction, but this movie is loosely based on a memoir of the same name by freelance radio producer Danny Wallace.
campaign

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

美国总统奥巴马以每年40万美元的收入高居榜首,同时还拥有5万美元的免税账目。国会最近一次给美国总统加薪是在2001年。
6.The Conjuring 2:The Enfield Poltergeist

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Last year was especially striking because global heat records were broken or tied in every month except January and April, researchers said.
John Hummel, chief investment officer for AIS Group, a fund manager with $400 million under management, said all the new sources of global oil are expensive to extract, and he sees U.S. shale output falling by 2015.
1) I make contact easily when I meet people 0 1 2 3 4

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

通过比较不同地区指定类别的生活成本,《经济学人智库》指出,亚洲城市在食品上的购买成本最高,其中韩国首尔的食品价格最高。欧洲城市则是在休闲娱乐用品上的成本最高。
以下国家在“2017年最佳国家“整体排名中相当亮眼 。这份排名意在衡量全球最大经济体。
infect+ion→传染;感化

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Transport Ministry spokesman Xu Chengguang told a news conference that no further signs of life had been found and the chance of finding anyone else alive was "very slim."
库苏马诺教授认为,这一切都表明,苹果正在加大开放度,包括允许开发者对其iOS软件进行更多定制。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

After weeks of nail-biting auditions and five days of tense semi-finals, Britain’s Got Talent picked one of the 11 acts to be the 2014 champion.
Trailing China in 2015 was the UK with $1.9 billion, Japan, $1.8 billion, India, $1.6 billion, and South Korea, $1.5 billion.
旅友们,注意啦!尽管你可能还没制定好旅行计划,但“2014年最佳旅游目的地榜单”已经新鲜出炉了。近日,著名旅行指南出版商孤独星球出版社发布了“2014最佳旅游”排行榜。下面我们就从排名前十的国家中挑选出一些目的地让你先睹为快。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

今年由美国电影学会的电影评审总监是Tom Pollock,担任电视剧评审总监的是Richard Frank。评审团的其他成员还包括Judd Apatow, Halle Berry, Jamie Lee Curtis, Leonard Maltin,来自知名大学的著作家,学者,公认的电影艺术家,还有像媒体NPR,Rolling Stone, TV Guide, 华盛顿邮报对于电视电影的评论家们。
complain

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

这个啤酒机能从下往上倒着灌满一杯好酒。
单词associate 联想记忆:
The report also found that the top cities in intellectual capital and innovation and technological readiness also achieved high scores in the overall ranking, a clear indication that technologically advanced cities were more likely to earn the title of "cities of opportunity".

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

“很显然,单独一个年度,即使是创记录的年度,不可能告诉我们很多关于气候变化趋势的东西,”德国波茨坦气候影响研究所地球系统分析部门主管斯德范·拉姆斯朵夫(Stefan Rahmstorf)说。“然而,有记录以来的最热年度是2014年、2010年和2005年的这个事实清楚地表明,全球变暖并没有‘在1998年停止’,像一些人喜欢错误地宣称那样。”

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

这将是一部非常有趣的电影,刻画出了美国队长与钢铁侠之间微妙的关系, 两人经常陷入信任危机。
两周后,伯恩海默等几十位著名的早期绘画大师作品交易商出席伦敦的夜间拍卖会。过去,他们通常会在这些拍卖会上购买一些作品,以备在第二年3月的荷兰马斯特里赫特欧洲美术博览会(Maastricht European Fine Art Fair)上展示。但是由于卖家们鼓励苏富比和佳士得报出更高的估价来争夺自己的拍品,所以拍卖行只针对少数富豪进行宣传,现场竞价十分冷清。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 调控加码 楼市“小阳春”难入夏
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

今年中国内地共有54所高校进入亚洲大学排行榜前300名。
The Magic are the single-most mystifying team in this entire exercise. They make little sense on paper or on the court.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

A combination of tax increases and spending cuts in 2013 shaved about 1.5 percentage points off annual economic growth, according to the Congressional Budget Office. Many forecasters expect the fiscal drag in 2014 to be one-third that amount, or less. 'You'll have more political certainty this year,' said Gregory Daco, a U.S. economist at Oxford Economics.
4=true

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 2016卫浴行业大事记回顾
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

该报告还指出,自2013年以来,中国已成为全球最大的工业机器人市场。并且在近年来,中国国内的供应商通过提供更多高端产品,正在向供应链上游进军。
*最佳真人秀主持:鲁保罗?查尔斯(RuPaul Charles),《鲁保罗变装皇后秀》(RuPaul’s Drag Race, Logo)

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

8.出租车司机

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Yes, 2014 is an absolute total disaster just waiting to ignite. In 'Doomsday poll: 87% risk of stock crash by year-end' we analyzed 10 major crash warnings since early this year. Since then, more incoming bogies raced across our radar screen. Ticking time bombs from Congress, the Supreme Court, sex, carbon emissions, Big Oil, NSA, IRS, Tea Party austerity. Relentless. Mind-numbing.
[n?t]
After the success of The Conjuring, Ed Warren and Lorraine Warren are back to kick some ghost butts. Conjuring 2 is based on the Enfield Poltergeist, which is apparently a true event that took place in London in 1977.
今年最佳的季中交易早已发生了:

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Wheel skates look somewhat like regular inline skates, except that the wheels are much larger, up to the size of bicycle tires. They are seen as a cross between an inline skate, a ski, and a bike. Recently, a company called Chariot Skates said they had come up with something unique—the Chariot wheel skates. According to the company, wheel skates are "revolutionary new skating products." Revolutionary? They do at least revolve. New? No. The first wheel skate was made more than 142 years ago.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

报告指出,大连万达集团主席王健林以321亿美元的个人财富荣登榜首,而马云的个人财富在2015年上涨了41%。
London Business School has topped the European table for the third year running — but continental rivals lead the European schools in the individual rankings used to compile it.
主机运营商HostGator.com公司的布兰迪o班奈特认为,在一家可靠的网站上坚持写博客,或者做一名志愿者,贡献出你的时间和技能。不要去告诉别人你是谁,而应该通过实际行动去展示你自己,这样做可以积累专业知识以及个人信誉。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 前三季度龙江关停50家家具企业
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

一家国际医学杂志撤销了107篇中国学术论文,由此引发了人们对中国学术诚信的关注。被撤稿的作者多数是临床医生。
"I'm always amazed at how many people tell their co-workers about their job search," Kay says. "That's one of the worst things you can do." Ideally, you wouldn't tell any co-workers, but you may have to if you want them to serve as references. In that case, Kay says, "you need to pick people who you really trust, who don't have a hidden agenda and who won't let it slip."

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

奥巴马将迎来第二个任期,摆在他面前的任务依然很艰巨:如何处理1万亿美元的高额年度财政赤字,如何削减高达16万亿美元的国债,如何改革开支高昂的社会事业,如何应对党派斗争激烈陷入僵局的美国国会等等。
35岁的阿德里亚娜·利马身着一件凸显身材的白色抹胸式礼服。这位巴西模特选择了简单又时髦的装扮,她把头发扎了起来,戴着一条抢眼的项链,项链上缀满了钻石。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 规范民宿应多一些“网约”思维
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

2016年,9个省级地区的GDP超过3万亿元,比上一年增加3个;25个省级地区的GDP突破1万亿元,与上一年持平。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

On Her Majesty's Secret Service gets an honorable mention on our list of James Bond Theme songs.
In this Sept. 18, 1990, file photo, Steve Jobs, president and CEO of NeXT Computer Inc., shows off his company's new NeXTstation after an introduction to the public in San Francisco
怎么挑染头发

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

007电影中,反派人物往往没有自己的主题曲,但是《金枪人》中克里斯多弗·李扮演的暗杀者出场时有一段轻快动人的绝妙曲调,衬托出暗杀者如地狱使者般帅气冷酷。LuLu的演唱完全演绎出这个反派斯卡拉孟加的过人之处。即使这首歌在今天来说欢快得有点可笑,但这也增添了它的魅力。
Moonlight, an evocative coming of age story about a young gay black man, won best picture at the 2017 Oscars but was almost denied its victory in chaotic scenes when the award was mistakenly given to La La Land.
May the beauty and joy of New Year remain with you throughout the new year!愿新春美景与欢乐常伴随你!
This year's lift was slower than the 6.5% rise in 2016, which is attributed to moderating economic growth and a rapidly aging society.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Among the top 50 richest women in the world, entrepreneurs from the Chinese mainland account for 56%.
剧情类最佳剧集:《权力的游戏》(Game of Thrones, HBO)

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Six regions recorded GDP growth less than 7 percent, with China's north-eastern rust belt Liaoning province at the bottom with negative growth.
"A total of 297 projects will be carried out in Tongzhou, such as building new subway lines and expressways, and improving ecologies," Lu Yan, director of the Beijing Municipal Commission of Development and Reform, said at a news conference on Wednesday.
历届“邦女郎”性感比拼

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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The seven large brick tombs were likelyconstructed for people of wealth, the researchers said.
7.Morocco

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